Method and intermediates for the preparation of derivatives...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C564S321000

Reexamination Certificate

active

08071788

ABSTRACT:
The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5 -difluorophenyl)methylsulfonamide.

REFERENCES:
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patent: WO 01/64634 (2001-09-01), None
patent: WO 02/28346 (2002-04-01), None
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Salehi et al., Facile Conversion of Alcohols into N-Substituted Amides by Magnesium Hydrogensulfate Under Heterogeneous Conditions, 2001, Synthetic Communications, 31(13), 1947-1951.
Formic acid [online], [retrieved on Mar. 17, 2011]. Retrieved from the Internet, URL:http://en.wikipedia.org/wiki/Formic—acid.
Gakhar, H.K., et al., A New Method of Preparation of 1,3-dioxolo[4,5-h] [1,4]Benzodiazepin-9-ones, Indian Journal of Chemistry vol. 34B, (1995) pp. 48-50.
Zubovics, Z., et. al.,, Synthesis and Antiarrhythmic Activity of N-aryl Alkylenediamines, Eur. J. Med. Chem. Ther. (1986) vol. 21, No. 5, pp. 370-378.
The Metabolic Syndrome, http://www.diabetes.org/weightloss-and-exercise/weightloss/metabollicsyndrome.jsp (2005).
Annual Update 2003/2004—Treatment of Neurological Disorders, Drugs of the Future (2004), vol. 29, No. 3, pp. 253-317.

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