Method and imaging system for imaging the spatial...

Details Method and imaging system for imaging the spatial... Method and imaging system for imaging the spatial...

2004-03-02

2009-06-09

Yun, Jurie (Department: 2882)

X-ray or gamma ray systems or devices

Specific application

Fluorescence

C378S004000, C378S006000, C378S062000

Reexamination Certificate

active

07545910

ABSTRACT:
The invention describes a method of generating metabolic images of an investigation region (3) of a body (1) by irradiating an X-ray fluorescence marker in that region and detecting the resulting X-ray fluorescence with a fluorescence detector (30). A fan beam (12) is used as a source of primary X-radiation, thus allowing the scanning of a whole body slice (3) in one step. The fluorescence image may be directly measured, e.g. by mapping voxels (104) of the investigation region onto pixels (134) of the detector (130) with the help of a pinhole collimator (132), or it may be reconstructed by procedures of computed tomography. Moreover, a morphological image may be generated by simultaneously recording X-ray transmission through the body (1).

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Q.Yu et al.: “Preliminary experiment of fluorescent X-ray computed tomography to detect dual agents for biological study”, J. Synchrotron Rad. (2001), pp. 1030-1034.
Takeda et al, “Fluorescent Scanning X-ray Tomography with Synchrotron Radiation”, Rev. Sci. Instrum. 66, Feb. 1995, pp. 1471-1473.
Takeda et al, “Human Thyroid Specimen Imaging by Fluorescent X-Ray computed Tomography with Synchrotron Radiation”, SPIE, vol. 3772, Jul. 1999, pp. 258-267.

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