Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1990-10-02
1992-03-31
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 46, 514286, 514837, 514851, 514867, 514869, A61K 912, A61K 31435
Patent
active
051006472
ABSTRACT:
Methods for the therapy of cystic fibrosis, Bartter's syndrome, and secretory diarrheas, and for diuretic treatment, by administering to a patient dodecahydro-7,14-methano-2H,6H-di-pyrido[1,2-a:1',2'-e][1,5]diazocine or a pharmaceutically acceptable derivative thereof are disclosed. The formulations include an aerosol formulation comprising the active ingredient in association with an aerosol propellant.
REFERENCES:
patent: 4415577 (1983-11-01), Hachmeister et al.
patent: 4501729 (1985-02-01), Boucher et al.
patent: 4866072 (1989-09-01), Edwards et al.
Pharmacognosy; 7th Ed., 1976, Lea & Febiger, pp. 287-288.
Levitan, Irwin B., Perspective, Jun. 23, 1989, p. 1423.
Knowles et al., New England Journal of Medicine, vol. 322, No. 17, pp. 1189-1194.
Jetten et al., Science, vol. 244, Jun. 23, 1989, pp. 1472-1475.
Boucher et al., J. Clin. Invest., vol. 84, Nov. 1989, pp. 1424-1431.
Berschneider et al., Faseb J., 1988 Jul. 2(10) Abstract.
Paolisso et al., Biochem. Pharmacol., 1985 Jul. 1;34(13) Abstract.
Paolisso et al., Horm. Metabol., 1988, pp. 658-659.
Dukes et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 254, No. 2, May 10, 1990.
Dubinsky, Hospital Practice, Jan. 15, 1989, pp. 69-82.
Hwang et al., Reports, Jun. 16, 1989, pp. 1351-1356.
Agus Zalman S.
Kelepouris Ellie
Morad Martin
Colucci D.
Page Thurman K.
The Trustees of the University of Pennsylvania
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