Chemistry: analytical and immunological testing – Peptide – protein or amino acid – Glycoproteins
Patent
1983-10-11
1986-02-04
Turk, Arnold
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
Glycoproteins
422 56, G01N 2178, G01N 3368
Patent
active
045686475
ABSTRACT:
Disclosed herein is an assay for determination of albumin in a liquid sample. This assay involves the use of a dye of the structure: ##STR1## wherein n is zero or a positive integer up to 3; R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen, alkyl, cycloalkyl, aryl, alkoxy, aroxy, hydroxy, carboxy, alkoxycarbonyl, amino or a nonaromatic heterocyclic group; and Z and Z.sub.1 independently represent the carbon, nitrogen, oxygen or sulfur atoms needed to complete a substituted or unsubstituted 5- to 7-membered carbocyclic or heterocyclic ring. This dye has a high affinity for albumin over a wide pH range. When the dye is bound to albumin, a shift in the dye spectral absorption occurs. Analytical elements containing this dye and an assay method are disclosed herein.
REFERENCES:
patent: 2241238 (1941-05-01), Brooker et al.
patent: 2553206 (1950-12-01), Dent, Jr. et al.
patent: 2897058 (1959-07-01), Galat
patent: 3359072 (1967-12-01), Rey et al.
patent: 3485587 (1969-12-01), Keston
patent: 3672845 (1972-06-01), Verbeck
patent: 4013416 (1977-03-01), Rittersdorf et al.
patent: 4230456 (1980-10-01), Wu
Nikolajewski et al., Chemical Abstracts, vol. 93, 1980, p. 214, No. 93:90449a.
Brooker et al., J.A.C.S., 73, p. 5332 (1951).
Sturmer et al., "The Theory of the Photographic Process", James (ed.), MacMillian Pub. Co., N.Y., 1977, pp. 194-196.
R. H. Henry et al., Clinical Chemistry Principles & Technics, pp. 449-451, Harper & Row, 1974.
Gustaffson, Clin. Chem., 22(5), pp. 616-622 (1976).
Webster, Clin. Chim. Acta, 53, pp. 109-115 (1974).
Eastman Kodak Company
Tucker J. Lanny
Turk Arnold
LandOfFree
Method and element for albumin assay does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and element for albumin assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and element for albumin assay will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2340806