Method and dosage form for treatment of premenstrual syndrome

Details Method and dosage form for treatment of premenstrual syndrome Method and dosage form for treatment of premenstrual syndrome

1989-10-27

1992-08-18

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514786, 424455, A61K 3156, A61K 4700, A61K 966

Patent

active

051400219

ABSTRACT:
A pharmaceutical composition suitable for oral administration comprises micronized progesterone in an oil vehicle which is high in glycerides of polyunsaturated fatty acids. Micronized progesterone particles suspended in such an oil vehicle are absorbed more readily into the bloodstream and achieve high progesterone blood serum levels. The pharmaceutical composition according to the invention can be readily formulated into capsules and administered for the treatment of premenstrual syndrome.

REFERENCES:
patent: 2577052 (1947-10-01), Himelick
patent: 2675342 (1950-09-01), Lee et al.
patent: 2988486 (1961-06-01), Masters et al.
patent: 3051624 (1962-08-01), Lozinski
patent: 3230142 (1966-01-01), Spero
patent: 3284303 (1966-11-01), Meli
patent: 3288679 (1966-11-01), Fried et al.
patent: 3342682 (1967-09-01), Erocoli
patent: 3409721 (1968-11-01), Applezweig
patent: 3535419 (1970-10-01), Siegrist et al.
patent: 3828106 (1974-08-01), Rudel
patent: 3862311 (1975-01-01), Leeson
patent: 3895103 (1975-07-01), Zaffaroni
patent: 4083973 (1978-04-01), van der Vies
patent: 4177267 (1979-12-01), Herschler
patent: 4189102 (1980-02-01), Andrews
patent: 4196188 (1980-04-01), Besins
patent: 4310510 (1982-01-01), Sherman et al.
patent: 4381298 (1983-04-01), Coulson
patent: 4522831 (1985-06-01), Chatterton, Jr.
patent: 4530839 (1985-07-01), Pasquale
patent: 4544544 (1985-10-01), Pasquale
Dennerstein et al., British Medical Journal, vol. 290, Jun. 1, 1985, pp. 1617-1621.
Reid and Yen, Am. J. Obstet. Gynecol., vol. 139, No. 1, pp. 88-104 (1981).
Coulson, Medical Hypotheses, 19:243-255 (1986).
Dalton, J. Steroid Biochem., vol. 20, No. 1, pp. 437-439 (1984).
Lyon et al., Journal of Reproductive Medicine, No. 10, pp. 705-711 (1984).
Maxson et al., Fertility and Sterility, vol. 44, No. 5, pp. 622-626 (1985).
Gonzalez, JAMA Medical News, vol. 245, No. 14 1394-1396 (1981).
Ferre et al., Am. J. Obstet. Gynecol., vol. 148, No. 1, pp. 26-34 (1984).
Whitehead et al., Obstetrical and Gynecological Survey, vol. 36, No. 1, pp. 31-33 (1981).
O'Brien et al., British Medical Journal, May 10, 1980, pp. 1161-1163.
Whitehead et al., British Medical Journal, Mar. 22, 1983, pp. 825-827.
Sampson, Brit. J. Pschiat., 135:209 at 215 (1979).
Van Der Meer et al., Journal of Psychosomatic Obstetrics and Gynaecology, vol. 2, No. 4, pp. 220-222 (1983).
Smith, Mood and the Menstrual Cycle, Topics in Psychoendocrinology, Chapter 2, pp. 19-58 (1975).
Morville et al., J. Gyn. Obst. Biol. Repr., 1982, 11, 355-363 (French; includes English abstract).
Ottosson et al., Acta. Obstet. Gynecol. Scand., 63:577-579 (1984).
Lane et al., British Medical Journal, vol. 287, pp. 1241-1245 (1983).
Kincl et al., Journal of Steroid Biochemistry, vol. 9, pp. 83-84 (1978).

Affiliated with

Also associated with

Rating

Method and dosage form for treatment of premenstrual syndrome does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and dosage form for treatment of premenstrual syndrome, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and dosage form for treatment of premenstrual syndrome will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1249202