Chemistry: analytical and immunological testing – Involving iga – igd – ige – or igm
Patent
1996-05-13
1999-10-19
Housel, James C.
Chemistry: analytical and immunological testing
Involving iga, igd, ige, or igm
436169, 435 11, G01N 33563
Patent
active
059688394
ABSTRACT:
A transport matrix and diagnostic device are provided which produce a physically detectable change in a predetermined distribution across a detection zone which correlates with the amount of selected analyte in a sample. The matrix includes a detection zone having a capture reagent yielding a physically detectable change which correlates with the amount of selected analyte in the sample. The detection zone has a leading boundary which first encounters the sample and a trailing boundary which encounters the sample after being transported across the detection zone. The capture reagent is immobilized on the matrix in a predetermined distribution from the leading boundary to the trailing boundary of the detection zone. A method is also provided which determines the level of a selected analyte in a sample by distributing a physically detectable change in a predetermined pattern across a detection zone on a transport matrix which correlates with the amount of selected analyte.
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Allen Michael P.
Blatt Joel M.
Patel Paul J.
Gens Timothy H.
Housel James C.
Metrika, Inc.
Portner Ginny Allen
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