Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-08-03
2009-11-03
Beisner, William H (Department: 1797)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C435S173700, C435S259000, C435S287200, C435S288500, C435S306100, C366S127000, C241S002000, C310S338000
Reexamination Certificate
active
07611840
ABSTRACT:
A device for sample tissue disruption and/or cell lysis comprising: a piezoelectric material; and at least a second material in contact with the piezoelectric material; and wherein the second material has an uneven surface on an opposite side to that in contact with the piezoelectric material. The device may be made by assembling at least three layers and membranes for the valves and pumps. The piezoelectric material is actuated by an external voltage source to generate cavitation, which disrupts tissue and/or lyses cells, in particular by a modulated alternative external voltage. The invention further provides a method of disrupting tissue and/or lysing cells in a device. Also provided is a piezoelectric device comprising a piezoelectric material in contact with a second material, and wherein the second material has an uneven surface on an opposite side to that in contact with the piezoelectric material.
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Mao Pei-Lin
Tay Eng Hock Francis
Xu Guolin
Yu Yuan Hong
Agency for Science Technology and Research
Beisner William H
Seed IP Law Group PLLC
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