Method and device for the detection of analyte in a fluid sample

Details Method and device for the detection of analyte in a fluid sample Method and device for the detection of analyte in a fluid sample

1997-11-10

2000-03-07

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

436525, 436815, G01N 33548, G01N 33553

Patent

active

060339187

ABSTRACT:
Disclosed is an improvement to the technique for immobilizing an analyte onto a solid surface for use in a competitive immunoassay. The improvement involves immobilizing the analyte on the solid surface by reacting the analyte or derivative thereof with polyethylene glycol which has been functionalized with a group which is reactive with the analyte contacting the resulting conjugate with the solid surface to thereby immobilize the analyte.

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S. Zalipsky, Bioconjugate Chem., vol. 6, pp. 150-165. Functionalized Poly(ethylene glycol) for Preparation of Biologically Relevant Conjugates, 1995.

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