Image analysis – Applications – Biomedical applications
Reexamination Certificate
2006-08-15
2006-08-15
Johns, Andrew W. (Department: 2624)
Image analysis
Applications
Biomedical applications
C359S368000
Reexamination Certificate
active
07092557
ABSTRACT:
The invention provides an apparatus for electromagnetically affecting a particle of interest in a specimen. The apparatus includes (a) a stage capable of supporting the specimen; (b) a detector including at least one camera, wherein the detector is capable of resolving a particle of interest within the specimen; (c) a means for locating the particle of interest in three dimensions; (d) a means for focusing electromagnetic radiation to a focal volume within the specimen; and (e) a means for adjusting the relative positions of the stage and electromagnetic radiation focusing means, thereby positioning the particle of interest within the focal volume.
REFERENCES:
patent: 3864571 (1975-02-01), Stillman et al.
patent: 4284897 (1981-08-01), Sawamura et al.
patent: 4395397 (1983-07-01), Shapiro
patent: 4532402 (1985-07-01), Overbeck
patent: 4629687 (1986-12-01), Schindler et al.
patent: 5013660 (1991-05-01), Kasuya et al.
patent: 5035693 (1991-07-01), Kratzer et al.
patent: 5072382 (1991-12-01), Kamentsky
patent: 5109276 (1992-04-01), Nudelman et al.
patent: 5235522 (1993-08-01), Bacus
patent: 5287272 (1994-02-01), Rutenberg et al.
patent: 5296963 (1994-03-01), Murakami et al.
patent: 5381224 (1995-01-01), Dixon et al.
patent: 5428690 (1995-06-01), Bacus et al.
patent: 5432865 (1995-07-01), Kasdan et al.
patent: 5552605 (1996-09-01), Arata
patent: 5590168 (1996-12-01), Iketaki
patent: 5646411 (1997-07-01), Kain et al.
patent: 5672880 (1997-09-01), Kain
patent: 5690846 (1997-11-01), Okada et al.
patent: 5713364 (1998-02-01), DeBaryshe et al.
patent: 5719391 (1998-02-01), Kain
patent: 5732150 (1998-03-01), Zhou et al.
patent: 5784162 (1998-07-01), Cabib et al.
patent: 5790710 (1998-08-01), Price et al.
patent: 5795755 (1998-08-01), Lemelson
patent: 5828776 (1998-10-01), Lee et al.
patent: 5891656 (1999-04-01), Zarling et al.
patent: 5932872 (1999-08-01), Price
patent: 5995143 (1999-11-01), Price et al.
patent: 6099522 (2000-08-01), Knopp et al.
patent: 6166385 (2000-12-01), Webb et al.
patent: 6804385 (2004-10-01), Eisfeld et al.
Bird et al., “4-Hydroperoxycyclophosphamide Purged Autologous Bone Marrow Transplantation in Non-Hodgkin's Lymphoma Patients at High Risk of Bone Marrow Involvement,”Bone Marr. Transplan.,18:309-313 (1996).
Clarke et al., “A Recombinant Bcl-XSAdenovirus Selectively Induces Apoptosis in Cancer Cells but Not in Normal Bone Marrow Cells,”Proc. Natl. Acad. Sci.,92:11024-11028 (1995).
Denk, “Two-Photon Scanning Photochemical Microscopy: Mapping Ligand-Gated Ion Channel Distributions,”Proc. Natl. Acad. Sci.,91:6629-6633 (1994).
Dooley et al., “A Novel, Inexpensive Technique for the Removal of Breast Cancer Cells from Mobilized Peripheral Blood Stem Cell Products,”Blood,88:252a, Abstract 995 (1996).
Gazitt et al., “Purified CD34+Lin-Thy+Stem Cells Do Not Contain Clonal Myeloma Cells,”Blood,86(1):381-389 (1995).
Grate and Wilson, “Laser-Mediated, Site-Specific Inactivation of RNA Transcripts,”Proc. Natl. Acad. Sci.,96:6131-6136 (1999).
Gribben et al., “Immunologic Purging of Marrow Assessed by PCR Before Autologous Bone Marrow Transplantation for B-Cell Lymphoma,”New Engl. J. Med.,325(22):1525-1533 (1991).
Gulliya and Pervaiz, “Elimination of Clonogenic Tumor Cells from HL-60, Daudi, and U-937 Cell Lines by Laser Photoradiation Therapy: Implications for Autologous Bone Marrow Purging,”Blood,73(4):1059-1065 (1989).
Jay, “Selective Destruction of Protein Function by Chromophore-Assisted Laser Inactivation,”Proc. Natl. Acad. Sci.,85:5454-5458 (1988).
Mapara et al., “Monitoring of Tumor Cell Purging After Highly Efficient Immunomagnetic Selection of CD34 Cells from Leukapheresis Products in Breast Cancer Patients: Comparison of Immunocytochemical Tumor Cell Staining and Reverse Transcriptase—Polymerase Chain Reaction,”Blood,89(1):337-344 (1997).
Mapara et al., “Combined Positive-Negative Purging and Transplantation of Peripheral Blood Progenitor Cell Autografts in Breast Cancer Patients: A Pilot Study,”Exper. Hemat.,27:169-175 (1999).
Oleinick et al., “The Photobiology of Photodynamic Therapy: Cellular Targets and Mechanisms,”Rad. Res.,150:S146-S156 (1998).
Palumbo et al., “Targeted Gene Transfer in Eucaryotic Cells by Dye-Assisted Laser Optoporation,”J. Photochem. Photobiol. B; Biol.,36:41-46 (1996).
Paulus et al., “Combined Positive-Negative Selection for Highly Effective Purging of PBPC Grafts: Towards Clinical Application in Patients with B-CLL,”Bone Marr. Transplan.,20:415-420 (1997).
Robertson et al., “Human Bone Marrow Depleted of CD33-Positive Cells Mediates Delayed but Durable Reconstitution of Hematopoiesis: Clinical Trial of MY9 Monoclonal Antibody-Purged Autografts for the Treatment of Acute Myeloid Leukemia,”Blood,79(9):2229-2236 (1992).
Theriot et al., “Comparison of Actin and Cell Surface Dynamics in Motile Fibroblasts,”J. Cell Biol.,119(2):367-377 (1992).
Tricot et al., CD34+THY+LIN- Peripheral Blood Stem Cells (PBSC) Effect Timely Trilineage Engraftment in Multiple Myeloma (MM),Blood,86:293a, Abstract 1160 (1995).
Wagner et al., “Isolation of Small, Primitive Human Hematopoietic Stem Cells: Distribution of Cell Surface Cytokine Receptors and Growth in SCID-Hu Mice,”Blood,86(2):512-523 (1995).
Eisfeld Timothy M.
Koller Manfred R.
Palsson Bernhard O.
Cyntellect, Inc.
Johns Andrew W.
LandOfFree
Method and device for selectively targeting cells within a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and device for selectively targeting cells within a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and device for selectively targeting cells within a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3700712