Method and device for providing nicotine replacement therapy tra

Details Method and device for providing nicotine replacement therapy tra Method and device for providing nicotine replacement therapy tra

1994-07-21

1997-02-18

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424447, 424449, A61F 1300

Patent

active

056039476

ABSTRACT:
A skin or buccal patch for providing nicotine replacement therapy which comprises a matrix type laminated composite in which the matrix is composed of a mixture of nicotine in a polymer wherein the amount of nicotine in the matrix, diffusion coefficient of nicotine in the matrix and the thickness of matrix are such that the release of nicotine is: (1) controlled by the patch; (2) rapid and at a relatively high flux over the prescribed wearing time of patch; and (3) such that a substantial proportion of the nicotine initially in the patch has been released at the end of the prescribed wearing time.

REFERENCES:
patent: 4496853 (1985-08-01), Bannon
patent: 4758434 (1988-07-01), Kydonieus et al.
patent: 4839174 (1989-06-01), Baker
patent: 4877618 (1989-10-01), Reed, Jr.
patent: 4943435 (1990-07-01), Baker
patent: 5004610 (1991-04-01), Osborne
patent: 5016652 (1991-05-01), Rose
patent: 5064654 (1991-11-01), Berner
patent: 5091186 (1992-02-01), Miranda et al.

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