Method and device for pharmacological control of spasticity

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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A61M 3100

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049329367

ABSTRACT:
A method and apparatus for pharmacological control of spastic urethral sphincters, particularly in patients with spinal cord injuries, includes a special monopolar electrode
eedle (30) adapted for insertion through a cystoscope (46) in electrical isolation therewith but connection with an electromyograph (12) for precise determination of injection sites so that a toxin, such as botulinum A, can be injected directly into skeletal muscle tissue, rather than connective tissue, to denervate and thus relax the sphincter.

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Lockart, et al., "Sphincterotomy Failure in Neurogenic Bladder Disease", The Journal of Urology, Jan. 1986; vol. 135, pp. 86-89.
Scott, Alan B., "Botulinum toxin Injection of Eye Muscles to Correct Strabismus", Trans Am. Ophthalmol. Soc., 1981, vol. 79, pp. 734-770.
Webster et al., Medical Instrumentation-Application and Design, 1978; pp. 250, 305-308.
Cromwell et al., Instrumentation For Health Care, 1976; pp. 308-310.
Toxicology Mechanisms and Analytical Methods, vol. 2, 1961; Bensley et al., "the Treatment of Acute Poisoning", p. 833.

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