Method and device for metal-mirror cryofixation of biomedical or

Details Method and device for metal-mirror cryofixation of biomedical or Method and device for metal-mirror cryofixation of biomedical or

1987-07-27

1988-05-24

Warner, Steven E.

Refrigeration

Processes

Deodorizing, antisepticizing or providing special atmosphere

62514R, F24F 316

Patent

active

047457643

ABSTRACT:
A method for metal-mirror cryofixation of bio-medical or similar technical specimens in which a specimen is brought into contact with a highly polished, cooled metal mirror in order to cool at least a marginal zone of the specimen suddenly to a low temperature. In order to avoid deformation of the specimen caused by freezing, provision is made, immediately after the first contact between the specimen and the metal mirror, to press the latter against one another by an additional independent force until the specimen is completely frozen. A cryofixation device for this purpose comprises a force generating device, for example, a separate power storage device (135) which, under control, functions after contact between the specimen (106) and metal mirror (102), in other words exerts the additional force between the specimen and the metal mirror (FIG. 7).

REFERENCES:
patent: 4302950 (1981-12-01), Sitte
patent: 4306425 (1981-12-01), Sitte et al.
patent: 4531373 (1985-07-01), Rubinsky
patent: 4563883 (1986-01-01), Sitte
patent: 4637226 (1987-01-01), Sitte

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