Chemistry: analytical and immunological testing – Including sample preparation
Reexamination Certificate
2006-09-12
2006-09-12
Warden, Jill (Department: 1743)
Chemistry: analytical and immunological testing
Including sample preparation
C436S179000, C436S180000, C436S043000, C436S052000, C436S164000, C436S165000, C436S166000
Reexamination Certificate
active
07105356
ABSTRACT:
Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of the discrete sensing areas, and provide selective contact of the discrete sensing areas with a sample fluid flow. Immobilization of a ligand upon the discrete sensing area, followed by selective contact with an analyte contained within the sample fluid flow, allows analysis by a wide variety of techniques. Sensitized sensing surfaces, and sensor devices and systems are also provided.
REFERENCES:
patent: 4022575 (1977-05-01), Hansen et al.
patent: 4056324 (1977-11-01), Gohde
patent: 4997278 (1991-03-01), Finlan et al.
patent: 5313264 (1994-05-01), Ivarsson et al.
patent: 5773298 (1998-06-01), Lynggaard et al.
patent: 6200814 (2001-03-01), Malmqvist et al.
patent: 286 195 (1988-10-01), None
patent: 469 377 (1992-02-01), None
patent: WO 90/05305 (1990-05-01), None
patent: WO 93/24231 (1993-12-01), None
patent: WO 94/27137 (1994-11-01), None
patent: WO 96/10178 (1996-04-01), None
patent: WO 96/35940 (1996-11-01), None
patent: WO 97/01087 (1997-01-01), None
Blankenstein and Larsen, “Modular Concept of a Laboratory on a Chip for Chemical and Biochemical Analysis,” Biosensors & Bioelectronics 13(3-4):427-438, 1998.
Blankenstein et al., “Flow Switch for Analyte Injection and Cell/particle Sorting,” Analytical Methods & Instrumentations, Special Issue .mu.TAS, pp. 82-84, 1996.
Davies and Skelton, “CRC Series in Chemistry and Physics of Surfaces and Interfaces,” CRC Press, Boca Raton, 1996, Chapter 4, “Flow Cell Design Considerations For SPR Measurements,” pp. 89-103.
de Mello, Andrew J., “CRC Series in Chemistry and Physics of Surfaces and Interfaces,” CRC Press, Boca Raton, 1996, Chapter 1, “Surface Analytical Techniques for Probing Biomaterial Processes,” pp. 1-41.
Duveneck et al., “Planar Waveguide Sensing Systems: A Combination of Highly Sensitive Transducers with Smart Fluidic Systems to a Tru .mu.TAS,” Analytical Methods & Instrumentations, Special Issue .mu.TAS, pp. 158-162, 1996.
Ekins, “Multi-analyte immunoassay,” Journal of Pharmaceutical & Biomedical Analysis 7(2):155-168, 1989.
Gooding et al., “Novel “Flow Injection” Channel Flow Cell for the Investigation of Processes at Solid/Liquid Interfaces. 2. Experiment,” J. Phys. Chem. B 101:182-188, 1997.
Hlady et al., “Spatially Resolved Detection of Antibody-Antigen Reaction on Solid/Liquid Interface using Total Internal Reflection Excited Antigen Fluorescene and Charge-Coupled Device Detection,” Biosensors & Bioelectronics 5:291-301, 1990.
Hlady, “Spatially Resolved Adsorption Kinetics of Immunogobulin G onto the Wettability Gradient Surface,” Applied Spectroscopy 45(2):246-252, 1991.
Larsen et al., “A Novel Design for Chemical and Biochemical Liquid Analysis System,” Analytical Methods & Instrumentation, Special Issue .mu.TAS, pp. 113-115, 1996.
Larsen et al., “Microchip Based Coulter Particle Counter,” Microstructure Bulletin No. 3, p. 6, Nov. 1997.
Microfabricated Fused Silica Flow Chambers for Flow Cytometry, http://www-mtl.mit.edu/MTL/Report94/MEMS/fused.html. [Accessed Jun. 4, 1998].
The Zeneca/SmithKline Beecham Centre for Analytical Science, http://www.achem.ic.ac.uk/. [Accessed Jun. 4, 1998].
Weigl and Yager, “Silicon-Microfabricated Diffusion-Based Optical Chemical Sensor,” at 3.sup.rd European Conference on Optical Chemical Sensors and Biosensors , Mar. 31-Apr. 3, 1996, Zurich, Switzerland, p. 236.
Malmqvist Magnus
Roos H{dot over (a)}kan
Sjödin H{dot over (a)}kan
Sjölander Stefan
St{dot over (a)}lberg Ralph
Biacore AB
Cross LaToya
Seed IP Law Group PLLC
Warden Jill
LandOfFree
Method and device for laminar flow on a sensing surface does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and device for laminar flow on a sensing surface, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and device for laminar flow on a sensing surface will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3524152