Chemistry: analytical and immunological testing – Oxygen containing – Carbonyl – ether – aldehyde or ketone containing
Patent
1986-12-22
1990-06-05
Warden, Robert J.
Chemistry: analytical and immunological testing
Oxygen containing
Carbonyl, ether, aldehyde or ketone containing
422 58, 422 61, 422 85, 422 86, 436130, G01N 3000, G01N 33497
Patent
active
049314041
ABSTRACT:
The present invention relates to methods and materials for the detection of ketone and aldehyde analytes in fluid samples by means of reacting analyte containing samples with a matrix comprising a hydrazine compound coupled to an H.sup.+ ion exchange resin to produce a hydrazone reaction product with a characteristic color. Methods are also provided for ascertaining the fat catabolism effects of a weight loss dietary regimen comprising determining the breath acetone concentration of the subject by means of contacting said breath with a device comprising an H.sup.+ ion exchange resin to which a hydrazine compound has been coupled and correlating the breath acetone concentration to a standard reflecting the effect on breath acetone of fixed rates of fat metabolism.
REFERENCES:
patent: 2186902 (1940-01-01), Fortune
patent: 2283262 (1942-05-01), Kamlet
patent: 4114422 (1978-09-01), Hutson
patent: 4397956 (1983-08-01), Maggio
patent: 4579826 (1986-04-01), Bolton et al.
Crofford et al., Trans. Amer. Clin. Climatol. Assoc., 88, 128 (1977).
Dubowski, Clin. Chem., 20, 966-972 (1974).
Eriksen, New Scientist, 381, 608 (1964).
Freund, Metabolism, 14, 985-990 (1965).
Goschke et al., Resp. Exp. Med., 165, 223-244 (1975).
Greenburg et al., J. Biol. Chem., vol. 154-155, 177 (1944).
Krotoszynski et al., J. Chrom. Sci., 15, 239 (1977).
Reichard et al., J. Clin. Invest., 63, 619-626 (1979).
Rooth et al., The Lancet, 1102-1105 (1966), 11/19/66.
Rooth et al., Acta. Med. Scand., vol. 187, pp. 455-463 (1970).
Walther et al., Acta Biol. Med. Germ., 22, 117-121 (1969).
Wynn et al., The Lancet, 482 (1985), 3/2/85.
Abbott Laboratories
Brainard Thomas D.
Corneglio Donald L.
Johnston Jill
Sharp Jeffrey S.
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