Method and device for isolation and/or determination of an...

Details Method and device for isolation and/or determination of an... Method and device for isolation and/or determination of an...

2002-09-12

2008-11-11

Warden, Jill (Department: 1797)

Chemistry: analytical and immunological testing

Including sample preparation

Stabilizing or preserving

C436S174000

Reexamination Certificate

active

07449341

ABSTRACT:
The invention concerns a method for isolating an analyte from an initial sample containing same, on a reactive surface in contact with all or part of the initial sample, characterized in that it comprises the following steps which consist in: 1) forming and/or maintaining a reaction volume entity, comprising an internal liquid medium, corresponding to all or part of the initial sample, the entity including an interface with an external medium, having with the latter a surface tension; 2) applying a temperature difference between at least two thermal points located: a) proximate to and/or b) on the surface and/or c) within said entity, said thermal points being respectively different, in terms of temperature and positioning; 3) fixing the analyte on the reactive surface, positioned on the path of forces convection generated by the temperature difference.

REFERENCES:
patent: 3807353 (1974-04-01), Kobernick
patent: 4672040 (1987-06-01), Josephson
patent: 5135048 (1992-08-01), Behrle et al.
Hanghui Liu, Purnendu K. Dasgupta, Analytical Chemistry in a Drop. Solvent Extraction in a Microdrop□□Analytical Chemistry, vol. 68, No. 11, Jun. 1, 1996.
Hanghui Liu, Purnendu K. Dasgupta, Analytical Chemistry in a Drop.□□Trends in Analytical Chemistry, vol. 15, No. 9, 1996.

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