Method and device for high speed separation of complex molecules

Details Method and device for high speed separation of complex molecules Method and device for high speed separation of complex molecules

1990-09-13

1993-12-14

Niebling, John

Chemistry: electrical and wave energy

Apparatus

Coating, forming or etching by sputtering

2041801, G01N 2726, G01N 27447

Patent

active

052699005

ABSTRACT:
A device and method useful for high-speed electrophoresis is disclosed. The device includes an on-column optical gating apparatus for high-frequency modulation of sample introduction, a variable resistance capillary, and a high voltage power supply to induce differential migration. The device separates charged molecules, including complex organic compounds, quickly and efficiently. The device can be used in multiplex chromatographic and electrophoretic separations.

REFERENCES:
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patent: 5110431 (1992-05-01), Moring
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Stephen L. Pentoney, Jr. et al "On-Line Connector for Microcolumns: Application to the On-Column o-Phthaldialdehyde Derivatization of Amino Acids Separated by Capillary Zone Electrophoresis" Analytical Chemistry 60 (1988) 2625-2629.

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