Method and device for determining local distribution of a...

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

Reexamination Certificate

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C600S322000

Reexamination Certificate

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06970729

ABSTRACT:
A system and method for determining the local distribution of measurement variables being measured relative to or present in a predefined measurement area of a biological sample wherein in a first optical measuring process the local distribution of a first of the measurement variables is determined using a sensor film applied to the measurement area and including a luminescence indicator reacting to the first measurement variable by a change of luminescence decay time. The luminescence decay time or a quantity derived therefrom is recorded by an imaging technique as a function of the first measurement variable. In a second optical measuring process the local distribution of a second of the measurement variables is determined simultaneously or immediately following, using an imaging technique which is effective through the sensor film of the first optical measuring process.

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P. Hartmann et al., “Fluorescence Lifetime Imaging of the Skin PO2Supply” in Oxygen Transport to Tissue XIX, New York, 1997, pp. 605-611.

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