Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...
Reexamination Certificate
2008-01-01
2008-01-01
Winakur, Eric F. (Department: 3768)
Surgery
Diagnostic testing
Measuring or detecting nonradioactive constituent of body...
C600S310000, C600S322000, C600S344000
Reexamination Certificate
active
07315752
ABSTRACT:
A method for the selective determination of the scattering index μsof a scattering biological matrix, in particular for the purpose of non-invasive determination of the concentration of glucose in the skin, by means of detection measurements, in each of which light in the form of primary light (9) is irradiated into the biological matrix (5) and an intensity measurement value of secondary light (12) exiting at a detection site (33-40) that is located at different measuring distances (ρ) from the respective light irradiation site (10) during the detection measurements is measured. In order to improve the quality and selectivity of the determination of μs, the primary light is irradiated obliquely at an angle between 5° and 85° using a contacting light-guiding element. In at least two detection measurements, the measuring distance (ρ) between the respective light irradiation site (10) and the respective detection site (33-40) corresponds to no more than five times the mean free path length of the light propagating in the biological matrix.
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Hein Heinz-Michael
Hermann Marcus
Kraemer Uwe
Baker & Daniels LLP
Lin Jack
Roche Diagnostics GmbH
Winakur Eric F.
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