Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-04-26
2005-04-26
Fredman, Jeffrey (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C422S082050, C422S082090
Reexamination Certificate
active
06884582
ABSTRACT:
The present invention relates to a method for detection of a molecular recognition reaction without labelling and a device for using this method.This invention concerns the general field of detection and analysis of molecular recognition between a first and a second molecule, for example a biological molecule.The method of the present invention consists of the detection of the molecular recognition by a photothermal method.
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patent: 6537801 (2003-03-01), Ida et al.
patent: WO 0020861 (2000-04-01), None
Milofsky et al, “Natie fluorescence detection of nucleic acids and DNA restriction fragments in capillary electrophoresis”, Analytical Chemistry (1993) 65:153-157.*
K. Adelhelm, et al. “Development of a Sensitive Detection System Based on the Photothermal Effect for Biomolecular Interaction Studies,” Biomedical Optoelectronics in Clinical Chemistry and Biotechnology, Sep. 14, 1995, vol. 2629, pp. 325-333.
Tamao Odake, et al., “High-Speed Separation Using Minaturized Slab Gel and High Spatial Resolution Detection by Thermal Lens Microscope,” Proceedings of the 1998 Thermal Therapy, Laser Welding and Tisue Interaction, Sep. 9, 1998, SPIE vol. 3565, pp. 126-133.
Takehiko Kitamori, “Chemistry and Analysis in Integrated Chemistry Lab on Chip,” Digest of Papers Nanotechnology, 1999, pp. 70-71.
Chaton Patrick
Ginot Frederic
Novelli Rousseau Armelle
Poupinet Ludovic
Biomerieux SA.
Commissariat a l''Energie Atomique
Fredman Jeffrey
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