Method and device for delivering fibrin glue

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530382, 604187, 604188, 604196, 2103216, 21032172, 21032174, 21032188, 21032189, 2104161, 21050026, 21050029, 21050034, 21050035, 422 99, 422101, 422102, A61K 3514, A61M 500, B01D 6300

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active

058440879

ABSTRACT:
A method and device for activating and applying a solution of fibrinogen to a desired site. The method includes contacting the solution of fibrinogen with immobilized thrombin resulting in an activated solution of polymerizable fibrin, and delivering the activated solution to the desired site. The device includes a housing having a compartment for a solution of fibrinogen, immobilized thrombin, a structure for bringing the solution of fibrinogen in contact with the immobilized thrombin under conditions which permit the activation of the fibrinogen resulting in polymerizable fibrin, and a structure for delivery of the activated solution to the desired site.

REFERENCES:
patent: 4359049 (1982-11-01), Redl et al.
patent: 4377572 (1983-03-01), Schwartz et al.
patent: 4642111 (1987-02-01), Sakamoto et al.
patent: 5290552 (1994-03-01), Sierra et al.
patent: 5393666 (1995-02-01), Linnau
patent: 5674394 (1997-10-01), Whitmore

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