Method and device for comprehensive two-dimensional gas...

Measuring and testing – Gas analysis – Gas chromatography

Reexamination Certificate

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C073S023350, C073S023370, C073S023400, C095S086000, C096S101000

Reexamination Certificate

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07107818

ABSTRACT:
A method for detecting substances or mixtures of substances within a sample in an apparatus for comprehensive two-dimensional gas-chromatographic analysis according to the present invention, comprising the steps of:subjecting the sample to a first separation within a first capillary column;modulating in time the effluents from the first column by means of the subdivision into adjacent fractions of the effluents from the first column and subsequently sending each fraction into a second capillary column, the modulation of the effluents being periodic with a first modulation frequency f1of the sample;separating each of the fractions in the aforesaid second capillary column; anddetecting, at the end of the second capillary column, the effluents by means of periodic sampling by discrete time points at a second frequency f2.The method moreover envisages the step of generating the first frequency f1of modulation and the second frequency f2of sampling in such a way that sampling by discrete points downstream of the second column will be in phase with the modulation of the effluents from the first column.

REFERENCES:
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patent: 5135549 (1992-08-01), Phillips et al.
patent: 5196039 (1993-03-01), Phillips et al.
patent: 5398539 (1995-03-01), Gordon et al.
patent: 5398593 (1995-03-01), Sirkis
patent: 5763283 (1998-06-01), Cernosek et al.
patent: 5929321 (1999-07-01), Bertrand
patent: 6632268 (2003-10-01), Seeley
patent: 2001/0037727 (2001-11-01), Ledford et al.
patent: 0 637 748 (1995-02-01), None
patent: 01/51179 (2001-07-01), None
Ledford et al. “J. High Resol. Chromatogr.”, vol. 23, Mar. 2000, p. 202-204.
Phillips et al; “Comprehensive Two-Dimensional Gas Chromatograpy: A Hypenated Method with Strong Coupling Between the Two Dimensions”; Journal of Chromatography A, Elsevier Science, NL, vol. 856, No. 1-2, Sep. 24, 1999, pp. 331-347, XP004180086.
Ledford et al., “J. High Resol. Chromatogr.”, vol. 23, Mar. 2000, p. 202-204.

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