Chemistry: analytical and immunological testing – Oxygen containing – Ozone or peroxide
Patent
1991-06-03
1996-07-30
McMahon, Timothy M.
Chemistry: analytical and immunological testing
Oxygen containing
Ozone or peroxide
436169, G01N 3352
Patent
active
055411150
ABSTRACT:
A test method and device employ a matrix to which is covalently bonded a second component of a two component dye system. Color is formed when the first component, which may be the analyte or another dye component, covalently couples to the second component. The color formed is covalently immobilized to the matrix. A preferred second component, 5-amino-2-naphthalene sulfonic acid, is covalently bonded via the amino group and forms a colored covalent adduct with oxidized 4-aminoantipyrine. Another preferred second component is diazotized para-aminoaniline, which is covalently bonded via the amino group and forms a colored covalent adduct directly with bilirubin.
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Georgevich Gradimir G.
Siegel Neal A.
Abbott Laboratories
McMahon Timothy M.
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