Method and container for reducing pertechnetate

Details Method and container for reducing pertechnetate Method and container for reducing pertechnetate

1980-02-25

1982-02-09

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

422 61, 423249, 424 9, A61K 4900, A61K 4300

Patent

active

043149863

ABSTRACT:
A method of reducing the pertechnetate in TcO.sub.4.sup.- comprises mixing together an aqueous solution of pertechnetate, e.g. the eluent from a technetium generator, metallic tin or an alloy thereof as a reducing agent for the pertechnetate, and a soluble salt of a metal below tin in the electrochemical series, e.g. copper, as an activator for the tin metal reducing agent. A complexing agent for the reduced technetium or a colloid stabilizer may also be included. The pH is preferably 3 to 12. Also claimed is a closed container containing the tin reducing agent, the activator, and the complexant or colloid stabilizer if used, preferably in a freeze-dried sterile state, to which the pertechnetate solution may be added.

REFERENCES:
patent: 3873680 (1975-03-01), Jackson et al.
patent: 3902849 (1975-09-01), Barak et al.
Persson et al., Int. J. App. Rad. Isot., vol. 28, 1977, pp. 97-104.

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