Method and constructs for inhibiting protein expression in bacte

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

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4352523, 4353201, 536 231, 536 241, 536 245, 536 251, C12N 1509, C12N 121, C07H 2102, C07H 2104

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059812800

ABSTRACT:
A method of inhibiting the translation of bacterial mRNA is disclosed, which method comprises overexpressing in a bacterium an mRNA which contains a sequence which is complementary to the anti-downstream box region of the 16S rRNA. RNA and DNA constructs for the overexpression of the mRNA of the invention are disclosed.

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