Image analysis – Applications – Biomedical applications
Patent
1998-02-23
2000-07-11
Chang, Jon
Image analysis
Applications
Biomedical applications
382156, 382168, 382199, 600408, G06K 962
Patent
active
060884738
ABSTRACT:
An automated method, and a computer storage medium storing instructions for executing the method, for analysis of image features in lung nodule detection in a chest radiographic image represented by digital data, including preprocessing the image to identify candidate nodules in the image; establishing a region of interest (ROI) including a candidate nodule identified in the preprocessing step; performing image enhancement of the candidate nodule within the ROI; obtaining a histogram of accumulated edge gradients as a function of radial angles withing the ROI after performing the image enhancement; and determining whether the candidate nodule is a false positive based on the obtained histogram. A 64.times.64-pixel region of interest (ROI) centered at the candidate location is used. The contrast of the ROI is improved by a two-dimensional background subtraction. A nodule shape matched filter is used for enhancement of the nodular pattern located in the central area of the ROI. Analysis of the histogram resulted in identification of seven features, including (1) a maximum histogram value, (2) a minimum histogram value, (3) a partial average value of the histogram, (4) a standard deviation of the histogram values near the radial axis, (5) a partial standard deviation of histogram values, (6) a width of the histogram including both sides from zero degrees of the radial angle, at a predetermined histogram value, and (7) a ratio of a maximum histogram value near the radial axis to a maximum histogram value in two predetermined outside ranges of the radial axis, useful for the identification and elimination of false positives.
REFERENCES:
patent: 4907156 (1990-03-01), Doi et al.
patent: 5289374 (1994-02-01), Doi et al.
patent: 5319549 (1994-06-01), Katsuragawa et al.
patent: 5343390 (1994-08-01), Doi et al.
patent: 5491627 (1996-02-01), Zhang et al.
patent: 5790690 (1998-08-01), Doi et al.
patent: 5832103 (1998-11-01), Giger et al.
X.W. Xu, K. Doi, T. Kobayashi, H. MacMahon, and M.L. Giger, "Development of an Improved CAD Scheme for Automated Detection of Lung Nodules in Digital Chest Images," Med. Phys. 24, 1395-1403 (1997).
X.W. Xu, H. MacMahon, M.L. Giger, and K. Doi, "Adaptive Feature Analysis of False Positives for Computerized Detection of Lung Nodules in Digital Chest Images" SPIE Medical Imaging 1997, Image Processing vol. 3034 428-436 (1997).
K. Doi, M.L. Giger, H. MacMahon, K.R. Hoffmann, S. Katsuragawa, R.M. Nishikawa, Y. Yoshimura, S. Sanada, X. Chen, C.E. Metz, C.J. Vyborny, R.A. Schmidt, S.M. Montner, T. Matsumoto, and K.G. Chua, "Computer-aided Diagnosis: Present and Future, A New Horizon on Medical Physics and biomedical Engineering", H. Abe, K. Atsumi, T. Iinuma, M. Saito, and M. Inoue, editors; Elsevier Science Publishers B.V. 1991.
K. Doi, M.L. Giger, R.M. Nishikawa, K.R. Hoffmann, H. MacMahon, R.A. Schmidt, and K.G. Chua, "Digital Radiography: A Useful Clinical Tool for Computer-aided Diagnosis by Quantitative Analysis of Radiographic Images," Acta Radiologica 34, 426-439 (1993).
M.L. Giger, K. Doi, and H. MacMahon, "Image Featrue Analysis and Computer-aided Diagnosis in Digital Radiography. 3. Automated Detection of Nodules in Peripheral Lung Fields," Med. Phys. 15, 158-166 (1988).
M.L. Giger, K. Doi, H. MacMahon, C.E. Metz, and F.F. Yin, "Pulmonary Nodules: Computer-aided Detection in Digital Chest Image," RadioGraphics 10, 41-51 (1990).
Y.C. Wu, K. Doi, M.L. Giger, C.E. Metz, and W. Zhang, "Reduction of False Positives in Computerized Detection of Lung Nodules in Chest Radiographs Using Artificial Neural Networks, Discriminate Analysis and a Rule-Based Scheme," J. of Digital Imag 7, 196-207 (1994).
Doi Kunio
Xu Xin-Wei
ARCH Development Corporation
Chang Jon
LandOfFree
Method and computer readable medium for automated analysis of ch does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and computer readable medium for automated analysis of ch, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and computer readable medium for automated analysis of ch will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-550108