Method and compounds for reducing dermal inflammations

Details Method and compounds for reducing dermal inflammations Method and compounds for reducing dermal inflammations

1987-07-20

1989-05-02

Lieberman, Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562426, 564154, 564163, 564170, 568 75, C07C14943, C07C14941

Patent

active

048270164

ABSTRACT:
Dermal inflammations which are induced and propagated by leukotrienes are treated by topically applying to the inflamed dermis the following compound: ##STR1## wherein R.sup.3 is H or a thiol; n is 1 to 12; p is 0 to 12; X is a substituted carbonyl, such as an ester or a carboxylic acid; and Y is an aliphatic or branched hydrocarbon, aromatic ring, carbonyl or substituted amide.

REFERENCES:
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patent: 4571430 (1986-02-01), Byrne et al.
patent: 4708965 (1987-11-01), Morgan
patent: 4721705 (1988-01-01), Schreuder
patent: 4724239 (1988-02-01), Morgan

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