Method and compounds for inhibiting lipid biosynthesis of bacter

Details Method and compounds for inhibiting lipid biosynthesis of bacter Method and compounds for inhibiting lipid biosynthesis of bacter

1996-08-21

1998-11-17

Leary, Louise

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

435 34, 435189, 435968, 435863, 435864, 435865, 435866, 435 4, 435 32, 435 71, 435 74, 514354, 536 237, 536 2433, 504716, 504117, C12Q 126, C12Q 104, C12Q 100, G01N 3353

Patent

active

058374809

ABSTRACT:
This invention relates to InhA enzyme crystals and to methods of growing said crystals. This invention is further directed to the utilization of said crystals to determine the three dimensional structure of InhA enzyme utilizing heavy atom derivatives of said crystals, and to the identification and development of compounds which inhibit the biochemical activity of InhA enzyme in bacteria and plants.

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