Method and compounds for diagnosing coronary artery disease

Details Method and compounds for diagnosing coronary artery disease Method and compounds for diagnosing coronary artery disease

1995-06-07

1998-07-07

Richter, Johann

Surgery

Truss

Pad

128898, 514597, 552 11, 558390, 564361, A61B 502, A61B 1900, C07C25508, A61K 3172

Patent

active

057753296

ABSTRACT:
The present invention relates generally to methods of diagnosis, evaluation and treatment of coronary artery disease in mammals using substituted catecholamines and compounds therefore. It also relates to the preparation, use and administration of these compounds which are useful in the diagnosis, evaluation and treatment of coronary artery disease by means of a feedback controlled drug delivery system that delivers exercise simulating agents which are capable of eliciting acute responses similar to those elicited by aerobic exercise.

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Young et al., Drug Dev. Res. 32:19-28 (1994).
Reitz, et al., J. Med. Chem. "Conjugates of Catecholamines. 6. Synthesis and .beta.-Adrenergic Activity of N-(Hydroxyalkyl)catecholamine Derivatives", 28(5):642-647, 1985.

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