Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-30
2007-10-30
Padmanabhan, Sreeni (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S314000
Reexamination Certificate
active
10369311
ABSTRACT:
This invention relates to a chemical compound that inhibits the apoptotic activity of the protease Omi/HtrA2 and homologous proteins. This protease Omi/HtrA2 is present in all mammalian cells so that inhibition of apoptosis in this fashion results enhanced cellular health and therapeutic effects.
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Hedge, Ramesh, et al., Identification of OMI/HtrA2 as a Mitochondrial Apoptotic Serine Protease that Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction,The Journal of Biological Chemistry, vol. 277, No. 1, Jan. 4, 2002, pp. 432-438.
Carter Kendra D
Engellenner Thomas J.
Nutter & McClennen & Fish LLP
Padmanabhan Sreeni
University of Central Florida
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