Method and compositions for treatment of parkinsonism syndrome i

Details Method and compositions for treatment of parkinsonism syndrome i Method and compositions for treatment of parkinsonism syndrome i

1988-06-13

1989-12-05

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3138

Patent

active

048853089

ABSTRACT:
This invention provides a method for treating the symptoms of parkinsonism which comprises administering to a human or other mammal suffering from the symptoms of parkinsonism an effective amount of a compound selected from the group consisting of optically-active or racemic compounds represented by the general formula: ##STR1## wherein R.sub.1 is selected from the group consisting of organic radicals methyl, substituted or unsubstituted phenyls, pyridyl, hydroxyphenyl, ##STR2## X is oxygen or sulfur, Y is selected from the group consisting of hydroxy, nitro, cyano, azido, amino, acylamino, carboxyamido, trifluoromethyl, sulfate, sulfonamido, halogen, hydrocarbyl and hetero atom-substituted hydrocarbyl radicals, wherein said heteroatoms are selected from the group consisting of halogen, nitrogen, oxygen, sulfur and phosphorus and said hydrocarbyl radicals comprise from 1 to 12 carbon atoms. and a is an integer of from zero to 3,

REFERENCES:
patent: 4564628 (1986-01-01), Horn
patent: 4657925 (1987-04-01), Horn
patent: 4722933 (1988-02-01), Horn
U.S. Patent Application Ser. No. 047,882 filed 5/8/87 for Method for Treating Schizophrenia.

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