Method and compositions for treating malignant tumors and inhibi

Details Method and compositions for treating malignant tumors and inhibi Method and compositions for treating malignant tumors and inhibi

1996-06-18

1998-06-02

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 23, 514 27, 536 41, A61K 3170

Patent

active

057600082

ABSTRACT:
According to the present invention, a substrate for cytochrome p450 which, after oxidation by cytochrome p450, reacts with thiol groups is conjugated to a saccharide to provide a tumor-specific compound which has low toxicity to normal cells. In one embodiment of the present invention, the saccharide conjugate of the cytochrome p450 substrate is administered in conjunction with a saccharide conjugate of a cytotoxic phenol, which provides a synergistic effect in destroying tumors.

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