Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1987-02-04
1988-12-13
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 9463, 514 17, A61K 3748
Patent
active
047909889
ABSTRACT:
Fibrinogen degradation product pentapeptide 6A and its variants are used in the treatment of thrombi, in particular myocardial infarcts. In a preferred embodiment pentapeptide 6A and tissue plasminogen activator are administered together to enhance the thrombolytic activity of tissue plasminogen activator.
REFERENCES:
patent: 4427646 (1984-01-01), Olexa et al.
patent: 4555290 (1984-06-01), Olexa et al.
patent: 4663146 (1987-05-01), Morser et al.
Thrombosis Research 30; 213-218, 1983, Andersson et al., American Physiological Society, pp. H457-H462, Mehta et al.
Biochimica et Biophysica Acta, 757(1983), pp. 366-370, Gerdin et al.
Prostaglandins Leukotrienes and Medicine 11, pp. 51-61, 1983, Hirose et al.
Prostaglandins Leukotrienes and Medicine 12j, 235-244, 1983, McDonald et al.
Chem. Abstracts, vol. 98, 1983, 193992e.
Chem. Abstracts, vol. 104, 1986, 101747v.
Chem. Abstracts, vol. 104, 1986, 45491t.
Chem. Abstracts, vol. 106, 1987, 38500h.
Biol. Abstracts, 73(6), 1982, 36910.
Mehta Jawahar L.
Saldeen Tom G. P.
Clarke Dennis P.
Phillips Delbert R.
University of Florida
Wessendorf T. D.
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