Method and compositions for suppressing allograft rejection in m

Details Method and compositions for suppressing allograft rejection in m Method and compositions for suppressing allograft rejection in m

1993-11-29

1997-10-28

Smith, Lynette F.

Drug, bio-affecting and body treating compositions

Lymphokine

424 852, 530395, 514 8, A61K 4505, A61K 3816, C07K 100, C07K 1400

Patent

active

056815565

ABSTRACT:
Disclosed herein are methods for suppressing allograft rejection in mammals comprising administering to a mammal about to undergo or having undergone allograft surgery an agent selected from the group consisting of splenic tissue from an allograft donor, splenic extracts, cultured lymphocytes from an allograft donor, extracts of said cultured lymphocytes, MHC antigens, transplantation rejection suppressive fragments and analogs of MHC antigens in an oral or aerosol form. Also disclosed herein are pharmaceutical formulations and dosage forms for use in said methods.

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