Method and compositions for solubilization and stabilization of

Details Method and compositions for solubilization and stabilization of Method and compositions for solubilization and stabilization of

1995-06-07

1998-03-24

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 852, 424 854, 424 856, 424 943, 514 2, 514 3, 514 12, 514 21, A61K 3817, A61K 3819, A61K 3820, A61K 3849

Patent

active

057309698

ABSTRACT:
The invention provides a method for the solubilization and/or stabilization of polypeptides, especially proteins, using a cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin. Solubilized and/or stabilized compositions comprising a polypeptide, especially a protein, and the selected cyclodextrin are also described.

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