Method and compositions for preventing and treating the systemic

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4241391, 4241441, 4241421, 4241581, 4241781, A61K 39395

Patent

active

059938110

ABSTRACT:
Administration of an antibody reactive to procalcitonin and/or its components is effective for the treatment and/or prevention of systemic inflammatory response syndrome (SIRS) and sepsis.

REFERENCES:
patent: 4277393 (1981-07-01), Sakakibara et al.
patent: 4493795 (1985-01-01), Nestor, Jr. et al.
patent: 5330909 (1994-07-01), Yamashita et al.
patent: 5639671 (1997-06-01), Bohvon
Hamilton G, et al., Scand. J. Infect. Dis., 1992; 24:361.
Bone RC, Crit. Care Med. 1996; 24:163.
Burrell R, Circ. Shock, 1994; 43:137.
Bahrami S, et al., Prog. Clin. Biol. Res., 1995; 392:197.
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference, Crit. Care Med., 1992; 20:864.
Bone RC, JAMA, 1995; 273:155.
Rangel-Fausto MS, et al., JAMA, 1995; 273:117.
Centers for Disease Control, MMWR, 1990; 39-31.
Lowry SF, Crit. Care Med., 1994; 22:S1-2.
Grabosch R, et al., Burns, 1992; 18:113.
Becker KL, et al., Anat. Rec., 1993; 236:136.
Becker KL, et al., "The Pathophysiology of Pulminary Calcitonin," in The Endocrine Lung in Health & Disease, Becker et al, Eds., W.B. Saunders, Philadelphia, pp. 277-299, 1984.
Snider, R et al., "Characterization of the hyperprocalcitonemia of inflammatory/infectious disorders," Am. Fed. Clin. Res., New Orleans, LA, Feb. 1, 1996.
Sperber SJ, et al., Rev. Inf. Dis., 1990; 12:736.
White J., et al, Pancreas Club, San Francisco, CA May 19, 1996.
O'Neill W., et al, J. Burn Care Rehab., 1992; 13:605.
Nylen ES, et al., Respir Med, 1995; 89:41.
Zeigler, EJ, et al, New Engl. J. Med., 1991; 324-429.
Natanson, C, et al., Ann Int Med, 1994; 120:771.
Suffredini, AF, Crit. Care Med., 1994; 22:S12.
Fisher, CJ, et al, New Eng. J. Med., 1996; 334:1697.
Eipper BA, et al., Annu. Neurosci., 1992; 15:57.
Becker KL, et al., in Principles and Practice of Endocrinology and Metabolism, 2.sup.nd ed., Becker KL, Ed., JB Lippincontt Co., Philadelphia, 1995, p. 474.
LeMoullec JM, et al., FEBS Lett, 1984; 167:93.
Mostov KE, Histol. Histopathol., 1995; 10:423.
Rothman JE, et al., FASEB J., 1990; 4:1460.
Steiner DF, et al., J. Biol. Chem., 1992; 267:23435.
Treilhou-Lahille F, et al., Biology of the Cell, 1986; 57:221.
Becker, KL, et al., Procalcitonin and its constituent peptides circulate in normal persons, 15.sup.th Joint Meeting of British Endocrine Societies, Dublin Ireland, Mar. 26, 1996.
Becker KL, et al., Acta Endocrinol., 1978; 89:89.
Becker KL et al., Surg. Gynecol. Obstet., 1982; 154:897.
Guilloteau D, et al., J. Clin. Endocrinol. Metab., 1990; 71:1064.
Motte P, et al., Clin. Chim. Acta., 1988; 174:35.
Seth R, et al., Horm. Metab. Res. Suppl., 1989; 21:3.
Weissel M, et al., Acta Endocrinol., 1991; 124:540.
Becker KL, et al., in Comparative Respiratory-Tract Carcinogenesis, Reznick-Schuller H, Ed., CRC Press, Boca Raton, FL, 1984; p. 161.
Becker KL, et al., Biochem. Pharmacol., 1985; 34:155.
Dandona, P. et al., J. Clin. Endocrinol. Metab., 79:1605-08, 1994.
Nylen, ES et al., Crit. Care Med., 25(8):1362-5, 1997.
Pahlke, K. et al., Intensivmedizin und Notfallmedizin, 34(5):381-387, 1997, Biosis Abstract Only, Accession No. 99708284.
Christman, JW et al., Critical Care Medicine, 23(5):955-963, 1995.
Quezado, ZMN et al., Trends in Biotechnology, 13(2):56-63, 1995.
Eichacker, PQ et al., Intensivmedizin und Notfallmedizin, 34(2):101-109.
Nylen, ES et al., Am. J. Med. Sci., 312(1):12-18, 1996.
Lynn WA et al., Clin. Infect. Dis., 20(1):143-58, 1995.
Becker KL et al., J. of Endocrinology, 152(Suppl), Abstract P145.
Mohamadi et al, "Paradoxical Effect of Parathyroid Hormone and Calcitonin on Serum Calcium in Man", pp. 657-660.
Silva et al, Geriatrics, vol. 28, p. 178(1973).
Silva et al, Arch. Intern. Med., vol. 132, pp. 337-339 (1973).
Wisneski et al, Clin. Pharmacol. Ther., vol. 24 (2), pp. 219-222 (1978).
Mohamadi et al, Acta Endocr., vol. 79, pp. 700-708 (1975).
Nylen et al, Crit. Care Med., vol. 26 (6), pp. 1001-1006 (1998).
Silva et al, Lancet, vol. 20, p. 763 (1972).
"Cibacalcin" from the Physicians' Desk Reference, pp. 889-890 (1993).
"Calcimar" from the Physicians' Desk Reference, pp. 1910-1911 (1993).
R. C. Bone et al, in Critical Care Medicine, vol. 17, pp. 389-393 (1989).
R. C. Bone in Infectious Disease Clinics of North America, vol. 5, pp. 793-805 (1991).
S. Rangel-Frausto et al, JAMA, vol. 273, pp. 117-123 (1995).
C. Brun-Buisson et al, in JAMA, vol. 274, pp. 968-974 (1995).
R. C. Bone et al, in Critical Care Medicine, vol. 23, pp. 994-1006 (1995).
Sepsis and Multiorgan Failure, Alan M. Fein et al, Eds., William & Wilkins, Baltimore, pp. 1 and 8, 1997.
Mastorakos G, et al., J. Clin. Endocrinol. Metab., 1994; 79:934.
Schutze, S, et al., Immunobiology, 1995; 193:193.
Madara JL, et al., J. Clin. Invest., 1989; 83;724.
Krieger DT, Clin. Res., 1983; 31:342.
LeRoith D, et al., Adv. Metabolic Disorders, 1983; 10:303.
Dunne, JR, et al., J. Surg. Res., 1996; 61:348.
Steinwald, P, et al., Intl. Congress Endocrinology, San Francisco, CA, Jun. 1996.
Becker KL, Chest, 1981; 79:211.
Kelley MJ, Am J Respir Crit Care Med, 1994; 149:183.
Chen D, et al., Biochem Pharmacol, 1995; 49:1623.
Abdullah SE, et al., Agents Actions, 1977; 7:533.
Aida S, et al., Ann Rheum Dis, 1994; 53:247.
Clopath P, et al., Prostaglandins, 1980; 19:1.
Edvinsson L, et al., J Cereb Blood Flow Metab, 1987; 7:720.
Silva OL, et al., Clin Chem, 1974; 20:337.
Silva OL, et al., Am J Med Sci, 1978; 275:159.
Becker KL, et al., Acta Endocrinol, 1979; 92:746.
Becker KL, et al., Experientia, 1980, 36:609.
Tashjian AH, et al., N Engl J Med, 1970; 283:890.
Snider RH, et al., Clin Chim Acta, 1977; 76:1.
Becker KL, et al., Cancer Lett, 1983; 18:179.
McMahon JL, et al., Lung, 1984; 162:261.
Becker KL, et al., Arch Pathol Lab Med, 1980; 104:196.
Nylen ES, et al., Peptides, 1987; 8:977.
Zhou A, et al., J Biol Chem, 1993; 286:1763.
Nylen ES, et al., Acta Physiol Scand, 1988; 132:117.
Linnoila RI, et al., Lab Invest, 1984; 51:39.
Aduen J, et al., Crit Care Med, 1995; 23-246.
Zaloga GP, et al., Ann Surg, 1985; 202:587.
Goldstein RA, et al., Univ Karlova Publ. Prague, 1971, p. 315.
Mohamadi M, et al., Acta Endocrinol, 1975; 79:700.
Gattereau A, et al., J Clin Endocrinol Metab, 1980; 51:354.
Gennari C, et al., Curr Therap Res, 1981; 30:1024.
Tabassian A, et al., Life Sciences, 1988; 42:2323.
Alam ASMT, et al., J. Endocrinol,1993; 136:7.
Salem M, et al., Crit Care Clin, 1991; 7:225.
Palmieri GM, et al., Endocrinology, 1969; 84:1509.
Weglicki WB, et al., Molec Cell Bioch, 1992; 110:169.
Yajnik CS, et al., BMJ, 1984; 288:1032.
Salem M, et al., Crit Care Med, 1995; 23:108.
Minne H, et al., Acta Endocrinol, 1973; Suppl 173:162.
Cantalamessa L, et al., Metabolism, 1978; 27:987.
Yamaguchi M,, Endocrinol Jpn, 1981; 28:643.
Hirata Y, et al., J Clin Endocrinol Metab, 1996; 81:1449.
Sugo S, et al., Biochem Biophys Res Commun, 1995; 207:25.
Nelkin BD, et al., Biochem Biophys Res Commun, 1984; 123:648.
Nuovo GJ, PCR in situ Hybridization, Raven Press, NY; Ch 5, 1992.
Knaus AW, et al., Crit Care Med, 1985; 13:818.
Colt EW, et al., Am J Clin Path, 1971; 55:40.
Gravel MR, et al., J. Bone Min Res, 1994; 9:1769.
Kelley M, et al., Cancer Lett, 1994; 81:19.
Selawry HP, et al., Horm Metab Res, 1975; 7:432.
Burgess TL, et al., Ann Rev Cell Biol, 1987; 3:243.
Becker KL, et al., "Calcitonin: Stricture, Molecular Biology, and Actions," in Principles of Bone Biology, Academic Press, New York, pp. 471-494, 1996.
Snider, Jr., et al, J. Investig. Med., 45:552-560 (1997).
Bedu et al, Serum Procalcitonin in Neonatal Sepsis, 37th ICAAC, Toronto, Canada, (1997).
Chiesa et al, Procalcitonin (PCT) as a Marker of Late-Onset Neonatal Infection, 37th ICAAC, Toronto, Canada (1997).
Oberhoffer et al, Clin. Intensive Care (Suppl.), 7:46 (1996).
de Werra et al, Crit. Care Med., 25:607-613 (1997).
Linnoila et al, Clinical Research, 30(1):434A (1982).
Christman et al, Crit. Care Med., 23:995-963 (1995).
Al-Nawas et al, Eur. J. Med. Res., 1:331-333 (1996).
Lynn et al, Clin. Infect. Dis., 20:143-58 (1995).
Eichacker et al, Intensivmed 34:101-109 (1997).
Davis et al, Trans. Roy. Soc. Trop. Med. Hyg., 88:670-671 (1994).
Gerard et al, Infection, 23:310-311 (1995).
Miller et

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and compositions for preventing and treating the systemic does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and compositions for preventing and treating the systemic, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and compositions for preventing and treating the systemic will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1668086

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.