Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-04-20
1998-06-09
Feisee, Lila
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 723, 435 71, 435 792, 435 794, 435 793, 435 795, 435 771, 435 79, 4241301, 4241381, 4241581, 5303871, 5303877, 53038823, G01N 3353, G01N 33573, C07K 1630, A61K 39395
Patent
active
057631956
ABSTRACT:
The complete amino acid and nucleotide sequence for adenylate cyclase stimulating factor is provided, thereby facilitating the synthesis of ACSF in recombinant cell culture. ACSF amino acid sequence variants and ACSF antibodies are provided which are useful in the treatment of humoral hypercalcemia of malignancy or in immunoassays for ACSF. In particular, antibodies capable of binding only the C-terminal domains of ACSF are useful in immunoassays for ACSF which avoid interference by parathyroid hormone. Also provided are novel polypeptides selected from the group of the ACSF basic peptide, the ACSF C-terminal peptide, or the ACSF domain containing both of the basic and C-terminal peptides.
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Martin Thomas John
Suva Larry John
Wood William I.
Feisee Lila
Genentech Inc.
Lucas John
University Of Melbourne
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