Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1992-12-22
1993-08-31
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 111, 536 41, 424717, A61K 3170
Patent
active
052409147
ABSTRACT:
The metabolism of tumor cells which have .beta.-glucuronidase activity is inhibited by administering to a patient a conjugate of glucuronic acid and a thiocarbamate compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are selected from the group consisting of C.sub.1 -C.sub.6 alkyl and C.sub.1 -C.sub.6 cycloaliphatic, and M is selected from the group consisting of hydrogen, an electropositive, ionically bonded metal, and the radical ##STR2## and R.sup.3 and R.sup.4 are selected from the group consisting of C.sub.1 -C.sub.6 alkyl and C.sub.1 -C.sub.6 cycloaliphatic groups.
REFERENCES:
patent: 4327074 (1982-04-01), Rubin et al.
patent: 4337760 (1982-07-01), Rubin
patent: 4424348 (1984-01-01), Rubin
patent: 4426372 (1984-01-01), Burch
patent: 4481195 (1984-11-01), Rubin
patent: 4584368 (1986-04-01), Rubin
patent: 4645661 (1987-02-01), Schonbaum
patent: 4762705 (1988-08-01), Rubin
patent: 4895874 (1990-01-01), Rubin et al.
patent: 4938949 (1990-07-01), Borch et al.
patent: 5002755 (1991-03-01), Mitchell et al.
patent: 5005588 (1991-04-01), Rubin
patent: 5035878 (1991-07-01), Borch et al.
Griffin Ronald W.
Rubin David
Schwimmer Adolph
LandOfFree
Method and compositions for inhibiting tumor cell metabolism does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and compositions for inhibiting tumor cell metabolism, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and compositions for inhibiting tumor cell metabolism will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2297385