Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds bacterium or component thereof or substance produced...
Reexamination Certificate
2002-01-25
2009-02-24
Graser, Jennifer E (Department: 1645)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds bacterium or component thereof or substance produced...
C424S130100, C424S139100, C424S150100, C424S164100, C530S387100, C530S388100
Reexamination Certificate
active
07494653
ABSTRACT:
A method of inhibiting, moderating or diagnosingPseudomonas aeruginosainfection is disclosed. In one embodiment, this method comprises inoculating a patient with an effective amount of PcrV antigen.
REFERENCES:
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Sawa T et al: “Active and passive immunization with the Pseudomnas V antigen protects against type II intoxcation and lung injury” Nature Medicine, Nature America, New York, US; vol. 5, No. 4, 1999; pp. 392-398; DXP002142838.
Holder I A et al: “Abstracts of the General Meting of the American Society for Microbiology, the Society, Washington, DC, US”; No. 100, 2000, pp. 279-280; XP008007075; ISSN: 1060-2011.
Kataoka T et al: “The Nucleotide Sequences of Rearranged and Germline Immunioglobulin VH Genes of a Mouse Myeloma MC101 and Evolution of VH Genes in Mouse”; Journal of Biological Chemistry vol. 257, No. 1, 1982; pp. 277-285; XP002213468; ISSN: 0021-9258.
Frank Data W et al: “Generation and characterization of a protective monoclonal antibody toPseudomopnas aeruginosaPcrV.” Journal of Infectious Diseases, vol. 186, No. 1; 2002, pp. 64-73; XP008007095; ISSN: 0022-1899.
Roggenkamp, A., et al. “Passive Immunity to Infection with . . . ”, Infection & Immunity, American Society for Microbiology, vol. 65, No. 2, Feb. 1997, 0019-9867.
European Search Report dated Feb. 2, 2008 issued in EP application 06000111.2-2402.
Frank Dara W.
Fritz Robert B.
Sawa Teiji
Wiener-Kronish Jeannine
Yahr Timothy L.
Graser Jennifer E
MCW Research Foundation, Inc.
Quarles & Brady LLP
The Regents of the University of California
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