Method and compositions comprising a vitamin D derivatives for t

Details Method and compositions comprising a vitamin D derivatives for t Method and compositions comprising a vitamin D derivatives for t

1989-07-26

1991-12-03

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424422, 514167, 514171, 623 16, A61F 200, A61K 3159

Patent

active

050699059

ABSTRACT:
A method for the treatment and promotion of healing of bone fractures and osteotomies in warm-blooded animals including humans, which comprises local application to the site of the fracture or osteotomy of a therapeutically effective amount of 24,25(OH).sub.2 D.sub.3 dissolved or dispersed in a suitable physiologically compatible carrier.
There are also provided, for use in the above method, compositions comprising from 0.002 to 0.2% by weight of 24,25(OH).sub.2 D.sub.3 in combination with a physiologically compatible vehicle suitable for use in orthopedic surgery for local application to a site of bone fracture or osteotomy, or for application to solid or semi-solid implants conventional in orthopedic surgery and to prostheses.

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