Method and composition of oxy-iron compounds for treatment of hy

Details Method and composition of oxy-iron compounds for treatment of hy Method and composition of oxy-iron compounds for treatment of hy

1989-06-05

1990-11-13

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Heavy metal or compound thereof

424647, 424648, A61K 3326

Patent

active

049700790

ABSTRACT:
Oxy-iron compounds are useful for the treatment and prevention of hyperphosphatemia. Such compounds, particularly those exhibiting high surface area, can be administered orally to bind and inhibit absorption of dietary phosphate, or such compounds can be contacted with the dialysate in a hemodialysis unit to enhance reduction of serum phosphate of patients undergoing hemodialysis.

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patent: 4668400 (1987-05-01), Veech
patent: 4870105 (1989-10-01), Fordtran
Mann et al., Formation of Iron Oxides in Unilamellar Vessicles. J. Colloidal Interface Sci. 122(2) 326-335 (1988).
Coburn, Jack W., M.D. and Isidro B. Salusky, M.D., "Control of Serum Phosphorus in Uremia", The New England Journal of Medicine, Apr. 27, 1989, pp. 1140-1142.
Stucki, J. W., B. A. Goodman and U. Schwertmann, "Iron in Soils and Clay Minerals", Published in cooperation with NATO Scientific Affairs Division.

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