Method and composition having enhanced alpha-hydroxy acid skin p

Details Method and composition having enhanced alpha-hydroxy acid skin p Method and composition having enhanced alpha-hydroxy acid skin p

1994-03-22

1995-05-30

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424401, 424443, 424445, 424447, 514 12, 514 19, 514844, 514887, 514947, A61K 700, A61K 3140

Patent

active

054201063

ABSTRACT:
Methods of enhancing skin permeation and skin retention of .alpha.-hydroxy acids for the treatment of dermatological disorders by applying a composition containing an amphoteric salt of an .alpha.-hydroxy acid, such as lactic, glycolic, citric, tartaric or malic acid and an amino acid, dipepdide, polypeptide or proteins, in a dermatologically acceptable carrier which contains 0.5 to 8% glycerol monocaprylate, 0 to 80% petrolatum and 0 to 30% isopropyl myristrate, the pH of the composition being from 3 to 9, and compositions for practicing such methods.

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patent: 5091171 (1992-02-01), Yu et al.
patent: 5254343 (1993-10-01), Parab et al.
patent: 5306729 (1994-04-01), Spiegelman et al.

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