Method and composition for treatment of gastric and duodenal dis

Details Method and composition for treatment of gastric and duodenal dis Method and composition for treatment of gastric and duodenal dis

1991-07-23

1993-06-29

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514926, 514927, A01N 3708

Patent

active

052235378

ABSTRACT:
The invention is related to the field of treating gastric and duodenal disorders and more specifically to the use of certain 13,14-dihydro-prostaglandin E derivatives, especially of PGE.sub.2, which are modified to contain a ring structure in the omega chain. The invention relates also to pharmaceutical compositions containing an active amount of these derivatives.

REFERENCES:
patent: 4820728 (1989-04-01), Collins
patent: 4833157 (1989-05-01), Kluender
Vincent et al. "11-substituted 11-deoxyprostaglandins . . . " Chem Abs. 87(5)39000 w of Fr. Demande 2301242 (1976).
Pfitzner J Am Chem Soc 87:5670-5678 (1965).
Corey J. Am Chem Soc 88:5654 (1966).
Brown J. Am Chem Soc. 94:7159-7161 (1972).
Yankee et al. Chem Abst. 88:62048x, 1978.
Bundy Chem Abst. 90:168141d, 1979.

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