Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Patent
1992-12-03
1995-07-18
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
424617, 424404, 424723, 514192, 514250, 514501, 514863, 420441, 423493, A61K 3324, A61K 3128
Patent
active
054339545
ABSTRACT:
Psoriasis, seborrheic dermatitis and eczema are treated by oral administration of inorganic nickel compound(s), with or without inorganic bromide(s). In an especially preferred embodiment, the nickel compound used to treat these diseases is NiBr.sub.2.
REFERENCES:
4, Cylopaedia & Medical Bulletin, pp. 348-355, "On the Uses of Nickel Sulfate in Medicine", by Louis Kolipinski, M.D. (1911).
The Merck Index, Windholz et al. editor, 10th Edition, Merck & Co., Rahway, N.J., 1983 pp. 932.
Weingartner et al., "Composition of the First . . . in Conc. Aqueous NiCl.sub.2 and NiBr.sub.2 Solutions", J. Chem. Soc., Faraday Trans., 1 75(12), 2700-11, 1978.
Sjovall, et al., "Oral Hyposensitization in Nickel Allergy", J. Amer. Acad. Dermatitis, V. 17, No. 5, Part 1, Nov. 1987.
Gawkrodger, et al., "Nickel Dermatitis: The Reaction to Oral Nickel Challenge;" Brit. J. Dermat., 115, pp. 33-38 (1986).
DaCosta, J. M., "Observations on the Salts of Nickel, Especially the Bromide of Nickel", The Medical News, vol. XLIII, No. 13 (1883).
Jordan, W., "Nickel Feeding in Nickel-Sensitive Patients with Hand Eczema", J. Am. Acad. Dermatol., vol. 1, No. 6 (1979).
Smith Lorraine J.
Smith Steven A.
Bembenick B.
Hollinden Gary E.
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