Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-12-05
1989-06-27
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514277, 514345, 514474, 514656, 514810, 514909, 514953, 514966, 514967, 424422, 424465, 424DIG15, A61K 3155, A61K 31435, A61K 3144
Patent
active
048430714
ABSTRACT:
Compositions and methods are disclosed for the treatment of obesity, depression, drug abuse, and narcolepsy. The compositions comprise a norepinephrine precursor such as L-tyrosine or L-phenylalanine in combination with a norepinephrine re-uptake inhibitor such as desipramine. In another embodiment of the invention, the compositions further comprise enzymatic cofactors for the biosynthesis of norepinephrine.
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patent: 4598094 (1986-07-01), Wurtman
The Merck Index, 9th ed., p. 1262, Nos. 9493 & 9494.
Goodman & Gilman, The Pharm. Basis of Theropeutics, 6th ed., 1980, pp. 1570, 71, 1577 and 1578.
Wurtman et al., Science, 185:183-184 (1974).
Giannini, A. J. et al., J. Clin. Pharmacol., 26:211-214 (1986).
Menon, M. K. et al., Eur. J. Pharmacol., 12:156-160 (1970).
Miller, S. C. et al., Neuropsychobiology 13:160-166 (1985).
Rollins John W.
Serotonin Industries of Charleston
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