Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1995-11-16
1997-07-22
Bawa, Raj
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424464, 514510, 514577, 514894, A61K 920
Patent
active
056501676
ABSTRACT:
Disclosed is a method of inhibiting hepatitis B infection by administering a therapeutically effective amount of a compound having the formula (Formula 1): ##STR1## wherein R1 is selected from the group consisting of H, lower alkanoyl, lower arylalkylacyl, arylacyl, and C-1-linked saccharide, and R2 is separately selected from the group consisting of H, lower alkyl, lower arylalkyl, aryl, and C-1-linked saccharide. The compounds may also be used to treat other conditions, such as inflammatory bowel disease, autoimmune diseases, transplant rejection, septic shock, and for protection against irradiation damage. Novel celastrol derivatives are also disclosed.
REFERENCES:
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Bawa Raj
DAWA Incorporated
Powers Vincent M.
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