Method and composition for the elimination of water from an anim

Details Method and composition for the elimination of water from an anim Method and composition for the elimination of water from an anim

1977-10-21

1984-09-11

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 41, 536 185, 536 56, 536106, 536112, 536103, 536120, C07H 3172

Patent

active

044709757

ABSTRACT:
It has been found that certain insoluble hydrophilic cross-linked polysaccharides are useful pharmaceutical agents in diverting water elimination from the renal route to the gastrointestinal route, and removing excess water from the body by the gastrointestinal route. These properties are of specific therapeutic value in the treatment of edema, water intoxication in chronic renal failure, in reducing the frequency of hemodialysis, and in the treatment of other forms of fluid retention such as congestive heart failure, cirrhosis of the liver, and other disorders associated with refractory swelling. Sephadex-brand insoluble hydrophilic, cross-linked dextrans are preferred in the practice of the invention.

REFERENCES:
patent: 3624209 (1971-11-01), Granatek et al.
patent: 3627872 (1971-12-01), Parkinson et al.
patent: 3865807 (1975-02-01), Narang et al.
patent: 3934007 (1976-01-01), Gussin et al.
patent: 3962429 (1976-06-01), Furuno et al.
patent: 3983232 (1976-09-01), Pekic et al.
patent: 4002173 (1977-01-01), Manning et al.
patent: 4070460 (1978-01-01), Gainer, Jr.
patent: 4076930 (1978-02-01), Ellingboe et al.

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