Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1982-11-18
1985-04-16
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
424 9, 2604297, 423 89, 423249, 423395, 423414, 423544, 423494, A61K 4300, A61K 4900
Patent
active
045115516
ABSTRACT:
The invention is a method for detecting the presence of or a predisposition to cancer in mammalian individuals. A trace element, specifically tin, is administered to the individual in the form of a radioactive isotope or a compound containing a radioactive tracer. The tin-bearing compound thereafter accumulates in the various bodily organs and is excreted. Indicative of the presence of cancer or a predisposition is the lack of accumulation of the radioactive tin compound in the thymus and lymphatic system of the mammal. By comparison of the radioisotope concentration in the urine and blood, the early detection of a precancerous or leukemic condition can be made. The method is applicable to a wide variety of mammals, including human beings.
REFERENCES:
CRC Manual of Nuclear Medicine Procedures, 3rd Ed., ed. Keyes, Jr., CRC Press, 1978, pp. 86-87.
Nuclear Medicine and Biology Advances, vol. 2, (Proc. of the Third World Congress or Nuclear Medicine and Biology, Aug. 29-Sep. 2, 1982, Paris) Pergamon Press, N.Y., 1983, pp. 1366-1368.
Medical Radionuclides: Radiation Dose and Effects, U.S. Atomic Energy Commission Technical Information Center, Oak Ridge, Tenn., 1972, pp. 185-206.
Recent Advances in Nuclear Medicine, (Proceedings of the 1st World Congress of Nuclear Medicine, Sep. 30-Oct. 5, 1974, Tokyo & Kyoto, Japan), Ohkawa Printing Co., Yokohama, Japan, 1974, pp. 648-650.
Isotopes in Biochemistry and Physiology, Pt. 2, (Proceedings of the 2nd U.N. International Conference on the Peaceful Uses of Atomic Energy, Sep. 1-13, 1958, Geneva), pp. 252-257.
Cardarelli Bernadette
Cardarelli Nathan
Nucker Christine M.
Unique Technologies, Incorporated
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