Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-08-29
2006-08-29
Mickelvey, Terry (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S320100, C435S371000, C435S372200, C536S023500, C536S025300
Reexamination Certificate
active
07097972
ABSTRACT:
This invention provides non-naturally occurring and isolated naturally occurring nucleic acid molecules which encode proteins designated pro-Yama, p11 Yama and p20 Yama. This invention also provides recombinant polynucleotides coding for these proteins. Also provided by this invention is a non-naturally occurring nucleic acid molecule encoding mutant CrmA protein and a dominant inhibitory Yama. Vectors and host cells containing these nucleic acid molecules are further provided. Methods of modulating a cellular function regulated by the Fas receptor pathway in a cell is provided herein. In one aspect, this method comprises introducing into the cell a nucleic acid molecule coding for a gene product having CrmA biological activity such as dominant inhibitory Yama or alternatively, the CrmA gene product.
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Marvich Maria
Medlen & Carroll LLP
Mickelvey Terry
Regents of the University of Michigan
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