Method and composition for reducing weight

Details Method and composition for reducing weight Method and composition for reducing weight

1982-02-10

1984-05-01

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 2700

Patent

active

044461380

ABSTRACT:
A method for reducing weight by the administration of L-Dopa or a stabilized form thereof with or without a decarboxylase inhibitor and Molindone wherein Molindone acts as a potentiator to enhance the weight reducing potency of L-Dopa in warm-blooded animals. The synergistic effect of the combination of L-Dopa and Molindone reduces the required dosage of the two drugs to levels which can be tolerated by higher forms of mammals, whereas individually the dosages required to reduce weight in higher mammals is not easily tolerated and may be toxic or lead to undesirable side effects.

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patent: 3939253 (1976-02-01), Bodor et al.
patent: 4035507 (1977-07-01), Bodor et al.
Chem. Abst. 82, 25910(c) (1975), Shibiaya.
Chem. Abst. 86, 25944(z) (1977), Moore et al.
Rivera-Calimlim et al. "Morphologic and Biochemical Changes in the Gut after Chronic Treatment with L-Dopa" J. of Pharm. & Exp. Therapeutics, 184:2 (1973), pp. 440-448.
Gardos et al. "Weight Reduction in Schizophrenics by Molindone" Amer. J. Psychiatry 143: Mar. 3, 1977, pp. 302-304.

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