Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2002-12-02
2009-10-06
Woodward, M P (Department: 1619)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S423000
Reexamination Certificate
active
07597903
ABSTRACT:
A medical device and a method for imparting antibacterial properties to the device, made from hydrophobic polymer, particularly to urinary latex catheters comprises treatment of the device by spreading, dipping or spraying and consequent drying with natural biodegradable polymers (A), composition including a cross-linking agent (B) for partial cross-linking the mentioned polymer and an anti-microbial agent compatible with A and B. The polymer may be from a group of polysachharides, for example polyglucosamine-chitosan. For partial cross-linking of the polymer substances having aldehyde groups such as glucose or evolving aldehydes such as hexamethylenetetramine or their mixtures are used. The polymer is able to form on the surface of the medical device a thin film that swells in wet or moisturized state once inserted into the body. In the swollen state it will gradually release an anti-microbial agent.
REFERENCES:
patent: 3497378 (1970-02-01), Johnson et al.
patent: 4515593 (1985-05-01), Norton
patent: 4539234 (1985-09-01), Sakamoto et al.
patent: 4592920 (1986-06-01), Murtfeldt
patent: 4605564 (1986-08-01), Kulla et al.
patent: 4612337 (1986-09-01), Fox, Jr. et al.
patent: 4675347 (1987-06-01), Mochizuki et al.
patent: 5019096 (1991-05-01), Fox et al.
patent: 5089205 (1992-02-01), Huang et al.
patent: 5525348 (1996-06-01), Whitbourne et al.
patent: 5599321 (1997-02-01), Conway et al.
patent: 5804318 (1998-09-01), Pinchuk et al.
patent: 5830883 (1998-11-01), Block et al.
patent: 5945457 (1999-08-01), Plate et al.
patent: 6039967 (2000-03-01), Ottoboni et al.
patent: 6042877 (2000-03-01), Lyon et al.
patent: 6228393 (2001-05-01), DiCosmo et al.
patent: 6624138 (2003-09-01), Sung et al.
patent: 6797743 (2004-09-01), McDonald et al.
patent: 2002/0034550 (2002-03-01), Quong
patent: 2002/0037874 (2002-03-01), Renier et al.
patent: 2002/0103526 (2002-08-01), Steinke
patent: 2002/0173775 (2002-11-01), Modak et al.
Ratner et al., Biomaterials Science: An Introduction to Materials in Medicine, 1996, Academic Press, p. 119.
“Antimicrobial”. Stedman's Medical Dictionary 27th Edition. Online. INternet. Accessed Feb. 14, 2006. <http://www.thomsonhc.com>.
“Antibacterial”. Stedman's Medical Dictionary 27th Edition. Online. INternet. Accessed Feb. 14, 2006. <http://www.thomsonhc.com>.
“Microbe”. Stedman's Medical Dictionary 27th Edition. Online. INternet. Accessed Feb. 14, 2006. <http://www.thomsonhc.com>.
Bach A. Clinical Studies on the Use of Antibiotic and Antiseptic Bonded Catheters to Prevent Catheter-related Infection, Zentralblatt für Bakteriologie, 1995. 283(2). pp. 208-214.
Kohnen W et al , “Polymer Materials for the Prevention of Catheter-related Infections”. Zentralblatt für Bakteriologie. 1995, 283(2). pp. 175-186.
Boswald M. et al , Antimicrobial Activity and Biocompatibility of Polyurethane and Silicone Catheters containing Low Concentrations of Silver: A New Perspective in Prevention of Polymer-associated Foreign-body-infections, Zentralblatt für Bakteriologie, 1995, 283(2), pp. 187-200.
Rosch W et al , “Catheter-Associated Infections in Urology: Possible Use of Silver-Impregnated Erlanger Silver Catheter”, Infection, 1999. 27 Suppl 1. S74-77.
Raad I et al., “Silver Iontophoretic Catheter: A Prototype of a Long-term Anti-infective Vascular Access Device”, The Journal of Infectious Diseases, Feb. 1996. 173(2). pp. 495-498.
Schierholz JM et al . “Investigation of a Rifampin, Fusidic-acid and Mupirocin Releasing Silicone Catheter”, Biomaterials, 1998. 19. pp. 2065-2074.
Kamal GD. et al , “Reduced Intravascular Catheter Infection by Antibiotic Bonding”. J A M A , 265, May 8, 1991, N 18, pp. 2364-2368.
Hashimoto H et al , “Basic Study on Antibacterial Urethral Catheter I, Development of a New Anti-bacterial Coating Material for Silicone Catheters”, Kansenshogaku Zasshi. May 2000. 74(5), pp. 431-440.
Hashimoto H. et al , “Basic Study on Anti-bacterial Urethral Catheter II, Potency of a New Anti-bacterial Catheter and its Durability in Experimental Models”, Kansenshogaku Zasshi. May 2000, 74(5), pp. 441-449.
Cho YH et al., “Prophylactic Efficacy of a New Gentamicin-releasing Urethral Catheter in Short-term Catheterized Rabbits”. British Journal of Urology International, Jan. 2001. 87 (1). pp. 104-109.
Pugach JL et al , Antibiotic Hydrogel Coated Foley Catheters for Prevention of Urinary Tract Infection in a Rabbit Model, Journal of Urology, Sep. 1999. 162 (3 Pt 1), pp. 883-887.
Johnson JR et al , “Activities of a Nitrofurazone-containing Urinary Catheter and a Silver Hydrogel Catheter against Multidrug-resistant Bacteria Characteristic of Catheter-associated Urinary Tract Infection”, Antimicrobial Agents and Chemotherapy, Dec. 1999, 43 (12), pp. 2990-2995.
Bach A et al . “Prevention of Bacterial Colonization of Intravenous Catheters by Antiseptic Impregnation of Polyurethane Polymers”. Journal of Antimicrobial Chemotherapy, May 1994. 33(5). pp. 969-978.
Maki DG et al . “Study of a Novel Antiseptic Coated Central Venous Catheter”. Critical Care Medicine, 1991, 19 (4) Suppl, S99.
Raad I et al , “The Broad-spectrum Activity and Efficacy of Catheters Coated with Minocycline and Rifampin”, The Journal of Infectious Diseases, 1996, 173, pp. 418-424.
Liedberg H. et al , “Silver Alloy Coated Catheters Reduce Catheter-associated Bacteriuria”. British Journal of Urology. 1990. 65. pp. 379-381.
Johnson JR et al , “Prevention of Catheter-associated Urinary Tract Infection with a Silver Oxide-coated Urinary Catheter: Clinical and Microbiologic Correlates”, Journal of Infectious Diseases, 1990, 162. pp. 1145-1150.
Saint S et al , “Preventing Catheter-related Bacteriuria: Should we? Can we? How?”, Archives of Internal Medicine, Apr. 26, 1999. 159. pp. 800-808.
Liedl B . “Catheter-associated Urinary Tract Infections”. Current Opinion in Urology 2001, Jan. 11 (1). pp. 75-79.
Ahearn DG et al., “Effects of Hydrogel/silver Coatings on In Vitro Adhesion to Catheters of Bacteria Associated with Urinary Tract Infections”. Current Microbiology. Aug. 2000, 41(2). pp. 120-125.
Godfrey H et al , “Catheterization and Urinary Tract Infections Microbiology”. British Journal of Nursing, Jun. 8-21, 2000, 9(11), pp. 682-684, 686, 688-690.
Morris NS. et al , “The Development of Bacterial Biofilms on Indwelling Urethral Catheters”. World Journal of Urology. Dec. 1999, 17 (6), pp. 345-350.
Kumamoto Y et al , “Comparative Studies on Activities of Antimicrobial Agents against Causative Organisms Isolated from Patients with Urinary Tract Infections” (1998) II Background of Patients. Japan Antibiotics, Apr. 2000. 43 (4), pp. 234-248.
Tyagi M et al . “Preparation and Anti-bacterial Evaluation of Urinary Balloon Catheter”. Biomedical Science Instrumentation. 1997. 33. pp. 240-245.
Sedor J et al , “Hospital-acquired Urinary Tract Infections Associated with the Indwelling Catheter”. Urological Clinique of North America. Nov. 1999. 26 (4), pp. 821-828.
Simhi E. et al , “Effect of the Adhesive Antibiotic TA on Adhesion and Initial Growth ofE colion Silicon Rubber”. FEMS Microbiol Lett, Nov. 2000. 1:192(1): pp. 97-100.
Riley DK et al , “A Large Randomized Clinical Trial of a Silver-impregnated Urinary Catheter: Lack of Efficacy and Staphylococcal Superinfection”, Am J Med. Apr. 1995. 98(4): pp. 349-356.
Rosinskaya Cecilia
Weinberg Amotz
Berrios Jennifer A
Pearl Cohen Zedek Latzer LLP
Shenkar College of Engineering and Design
Woodward M P
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